Global inflation has a significant impact on the economies of developing countries, with effects that can be felt in various sectors. Amid instability in prices of goods and services, developing countries face complex challenges, making them vulnerable to fluctuations that occur in international markets. One of the direct impacts of global inflation is an increase in import costs. Developing countries often depend on imported goods, especially raw materials and energy. When inflation pushes the prices of these goods up, domestic production costs rise. As a result, local companies have to increase the selling prices of their products to maintain profit margins, which could lead to further inflation in the country. On the other hand, high global inflation often results in the strengthening of the currencies of developed countries. This adds pressure to emerging market currencies, causing greater depreciation. This exchange rate instability makes financial and investment planning difficult, especially for sectors that depend on foreign loans denominated in foreign currencies. The social health impact is also worth paying attention to. Rising food and energy prices can worsen poverty in developing countries. Many families in developed countries already have difficulty meeting basic needs, and inflation will only make this situation worse. In the long term, rising costs of living could increase levels of social dissatisfaction and protest, potentially destabilizing political stability. Foreign direct investment (FDI) is also affected by the global inflation situation. Investors tend to avoid countries with high inflation because of the uncertainty that accompanies them. This leads to reduced capital flows which are very important for economic growth in developing countries. A lack of investment can hinder innovation and infrastructure development, which are necessary for long-term competitiveness. Developing country governments are often caught in a monetary policy dilemma. To control inflation, the central bank may decide to raise interest rates. However, this policy can hamper economic growth, increase the debt burden, and reduce people’s access to loans. On the other hand, keeping interest rates low to support growth can exacerbate inflation, creating a cycle that is difficult to break. The agricultural sector is also a target for global inflationary forces. Rising fertilizer prices and other costs directly impact agricultural output, undermining food security. Uncertainty in food prices can affect people’s welfare, especially in countries with populations that rely heavily on subsistence agriculture. In addition, the tourism sector, which is the main source of income in several developing countries, is also suffering from global economic uncertainty. When inflation eats away at people’s purchasing power, citizens of developed countries tend to reduce spending on international travel. This reduces tourist visits and disrupts local income that could be used for development. Climate change and the uncertainty created by inflation also increase the economic vulnerability of developing countries. Frequent natural disasters, such as floods and droughts, can be exacerbated if communities do not have good economic resilience. High inflation reduces government capacity to invest in important mitigation and adaptation programs. In facing this challenge, developing countries need to implement a comprehensive strategy to mitigate the impact of global inflation. Diversifying economic resources, promoting innovation, and establishing wider trade networks can help them reduce dependence on volatile global markets. Through these strategic steps, developing countries can strengthen their position in an increasingly competitive global economic arena.